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[Two-stage nephron-sparing surgery for bilateral T2 renal cell carcinoma and von Hippel-Lindau disease: a case report] Hinyokika kiyo. Acta urologica Japonica [Hinyokika Kiyo] Journal article

 
Iguchi R, Kanematsu A, Nakamura E, Shimizu T, Watanabe J, Soda T, Kamba T, Yoshimura K, Nishiyama H, Kamoto T, Ogawa O 
[Two-stage nephron-sparing surgery for bilateral T2 renal cell carcinoma and von Hippel-Lindau disease: a case report] [English Abstract, Journal Article]
Hinyokika Kiyo 2009 Aug; 55(8):483-5.


A 32-year-old man was referred to our hospital for evaluation of bilateral renal tumors 8 cm each in diameter. His cousin also had a renal tumor, and she had been genetically diagnosed as von Hippel-Lindau (VHL) disease. Bilateral nephron-sparing surgery was performed in separate stages under clinical diagnosis of renal cell carcinoma and VHL disease. Histological examination revealed clear cell renal cell carcinoma (pT2). There was no evidence of local recurrence or metastasis 6 months after the second operation. In the treatment of renal cell carcinoma and VHL disease, nephron-sparing surgery is recommended to achieve a disease-free status without renal replacement therapy.



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